منابع مشابه
Tissue Proteins and Carcinogenesis
It has been known that certain azo dyes will produce cancer of the liver. During the precancerous stages the liver appears to undergo some definite changes. The activity of these azo dye carcinogens is influenced by several dietary factors. Thus the liver can be protected partiahy from the effects of the dye by simultaneous intake of increased amounts of riboflavin (1). This conforms with the f...
متن کاملThe CCN family proteins in carcinogenesis.
The CCN (Cyr61 (cysteine-rich protein 61), CTGF (connective tissue growth factor), Nov (nephroblastoma overexpressed)) family consists of six members that belong to matricellular proteins of extracellular matrix (ECM). Like other matricellular proteins, CCN members do not primarily have a structural role; however, they modulate cell-ECM interactions. In general, CCN proteins are formed by four ...
متن کاملRole of S100 Proteins in Colorectal Carcinogenesis
The family of S100 proteins represents 25 relatively small (9-13 kD) calcium binding proteins. These proteins possess a broad spectrum of important intracellular and extracellular functions. Colorectal cancer is the third most common cancer in men (after lung and prostate cancer) and the second most frequent cancer in women (after breast cancer) worldwide. S100 proteins are involved in the colo...
متن کاملReview Helicobacter pylori in Tonsillar and Adenoid Tissue and Its Possible Role in Oropharyngeal Carcinogenesis (Helicobacter pylori / carcinogenesis / oropharyngeal carcinoma / tonsillar tissue / adenoid tissue)
Helicobacter pylori is a well-known gastric pathogen. It plays a major role in the pathogenesis of chronic gastritis, duodenal and gastric ulcers, adenocarcinoma and gastric lymphoma. HP infection is one of the most common bacterial infections worldwide. Recently, the oral cavity was proposed as an extragastric reservoir of HP infection. HP was detected by culture and PCR in both dental plaque ...
متن کاملThe dual nature of Notch in tissue homeostasis and carcinogenesis
The Notch pathway is an evolutionarily conserved signaling system that plays a critical pleiotropic role in regulating stem cell self-renewal and differentiation. The functional outcome of Notch signaling is highly dependent on cellular context and signal dosage. For example, distinct levels of Notch activity can either promote or suppress proliferation of mammary gland epithelial cells. In add...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1949
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)57095-2